| Item Type | Name |
|
Academic Article
|
Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression.
|
|
Academic Article
|
Molecular mechanisms and biological significance of CTL avidity.
|
|
Academic Article
|
High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation.
|
|
Academic Article
|
Modulation of CD8+ T cell avidity by increasing the turnover of viral antigen during infection.
|
|
Academic Article
|
Abortive versus productive viral infection of dendritic cells with a paramyxovirus results in differential upregulation of select costimulatory molecules.
|
|
Academic Article
|
Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation.
|
|
Academic Article
|
Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells.
|
|
Academic Article
|
Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen.
|
|
Academic Article
|
Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection.
|
|
Academic Article
|
Specific prolongation of allograft survival by a T-cell-receptor-derived peptide.
|
|
Academic Article
|
Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones.
|
|
Academic Article
|
An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.
|
|
Academic Article
|
High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5.
|
|
Academic Article
|
Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity.
|
|
Academic Article
|
Ligation of CD80 is critical for high-level CD25 expression on CD8+ T lymphocytes.
|
|
Academic Article
|
Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus.
|
|
Academic Article
|
Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.
|
|
Academic Article
|
Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction.
|
|
Academic Article
|
Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma.
|
|
Academic Article
|
Molecular analysis of presentation by HLA-A2.1 of a promiscuously binding V3 loop peptide from the HIV-envelope protein to human cytotoxic T lymphocytes.
|
|
Academic Article
|
Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.
|
|
Concept
|
Antigen Presentation
|
|
Concept
|
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
|
|
Concept
|
HLA-A2 Antigen
|
|
Concept
|
Receptors, Antigen, T-Cell, alpha-beta
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
Antigen-Presenting Cells
|
|
Academic Article
|
High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.
|
|
Academic Article
|
CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals.
|
|
Grant
|
Control of T cell response during respiratory infection
|
|
Grant
|
Control of cytotoxic T cell differentiation and activity
|
|
Grant
|
CTL AVIDITY AND THE AGING IMMUNE RESPONSE
|
|
Academic Article
|
TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint.
|
|
Academic Article
|
Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response.
|